Phospho-histone h3 s10

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August undefined, 2024

WebDec 22, 2005 · For example, heterochromatin protein 1 (HP1) binds to histone H3 when its lysine 9 residue has been tri-methylated by the methyltransferase Suv39h (refs 2-6). During mitosis, H3 is also phosphorylated by the kinase Aurora B. Although H3 phosphorylation is a hallmark of mitosis, its function remains mysterious. WebPhospho-histone-H3 (PHH3) is a core histone protein, which in its phosphorylated state forms the principal constituents of eukaryotic chromatin, with histone H3 being phosphorylated at serine (Ser) 10 or Ser28 as well as its phosphorylation of Ser10 being strongly correlated with the late G2 to M-phase transition in mammalian mitotic cells.

Phospho-Histone H3-S10 Rabbit pAb (AP0840) - abclonal.com

WebAnti-phospho-Histone H3 (Ser10) Antibody, clone 3H10 is a mouse monoclonal antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as … WebThis antibody is specific for Histone H3 phosphorylated at residue Ser 28 and does not recognise the unmodified residue or another phosphorylated residue (Ser 10) on the same histone. Tested applications Suitable for: WB, PepArr, ICC/IF more details Species reactivity Reacts with: Human, Recombinant fragment ct 船

Anti-phospho Histone H3 S10 Antibody, clone 63-1C-8 , ZooMAb

WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometry and immunofluorescent analysis in human and mouse cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-Histone H3 (Ser10) Antibody #9701. WebSep 15, 2003 · Phosphorylation of Ser10 in the tails of histone H3 has been extensively studied in many organisms. Interestingly, this modification is involved in both … WebHistone H3 phospho S10 Antibody Rabbit Polyclonal Item No. 600-401-I74 Size: 50 µg Applications: Dot Blot, IF, WB Reactivity: C. elegans, Human Host Species: Rabbit Have a … ct 膀胱画像

Phospho-Histone H3 (Ser10) Antibody (MA5-15220)

WebPhospho-Histone H3 (Ser10) (6G3) Mouse mAb detects endogenous levels of histone H3 only when phosphorylated at serine 10. The antibody does not cross-react with other … WebPHH3 showed 0 to 16 mitoses/10 HPFs (mean, 3.8) in the STUMP group and 0 to 61 mitoses/10 HPFs (mean, 26) in the LMS group. In 7 cases, the MI difference (MID) between H&E-stained and PHH3-stained slides varied from 0 to 3 mitoses (mean, 1.6). In only one LMS, the PHH3 MI was lower than on H&E-stained slides (MID 7). ct 船種WebHistone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified ... ct 蓄電池

"WebDetection of Phospho Histone H3 (pS10). Asynchronous Jurkat cells were fixed in 1.5% PFA and permeabilized in 90% methanol. 1 x 10^6 cells were stained with 0.4 µg anti-phospho Histone H3 (S10) (Product # 301-844A) in a 150 µL reaction. " - Phospho-histone h3 s10

Phospho-histone h3 s10

WebAnti-Histone H3 (phospho S10) antibody [EPR17246] - ChIP Grade (ab177218) Research with confidence – consistent and reproducible results with every batch Long-term and … Web11 rows · Anti-phospho-Histone H3 (Ser10) Antibody, Mitosis Marker is a Rabbit Polyclonal Antibody for detection of Histone H3 phosphorylated at serine 10.This highly published …

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WebHistone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in … WebOct 27, 2016 · Histone H3 phosphorylation on serine-10 is specific to mitosis and phosphorylated histone H3 (PHH3) proliferation markers (as counts defined per area or as indices defined per cell numbers) are increasingly being used to evaluate proliferation in various tumors. Herein, we review current data on PHH3 proliferation markers in …

WebFeb 1, 2005 · The dynamic distribution of phosphorylated Histone H3 on Ser10 (phospho-H3) in cells was investigated to determine its function during mitosis. Human breast adenocarcinoma cells MCF-7, and Chinese ... WebThe Phospho-Histone H3 (Ser10) assay enables the detection of Ser10 phosphorylation in the tails of Histone H3, a key regulator of gene expression and mitosis. Phosphorylation …

WebAnti-phospho-Histone H3 (Ser10) Antibody, clone 3H10 is a mouse monoclonal antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p, is published in peer reviewed journals and has been validated in FC, ICC, IF, PIA, WB, Mplex. Flow Cytometry: WebOct 14, 2024 · Phosphorylation of serine 10 on histone H3 (H3S10ph) is an unique histone modification as it is involved in two structurally opposed processes: transcriptional activation and chromatin relaxation, or chromosome compaction during cell division [ 7, 8, 9, 10, 11, 12, 13, 14 ].

WebTested applications: WB IHC IF/ICC Reactivity: Human, Mouse, Rat, Other (Wide Range) Western blot analysis of extracts of various cell lines, using Phospho-Histone H3-S10 Rabbit mAb (AP0002) at 1:1000 dilution.HeLa, NIH/3T3 and C6 cells were treated by nocodazole (50 ng/mL) at 37℃ for 20 hours or treated by CIP (20uL/400ul) at 37℃ for 1 …

WebFeb 13, 2024 · The increase in pH i increases ROS production and promotes histone H4 cleavage. Collectively, the increase in ROS and H4 cleavage regulate the pH-dependent … ct 薄层WebAnti-Histone H3 (phospho S10) antibody [EPR17246] - ChIP Grade (ab177218) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast production Success from the first experiment – confirmed specificity through extensive validation ct 蓄膿症WebHistone H3 Phospho (S10) Reactivity: Human , Mouse Application: Flow Cyt , ICC-IF , IHC , WB Host: Rabbit Format: Whole IgG Immunogen: surrounding serine 10 Isotype: IgG Purity: Antigen Affinity Purified 100 µl (200 µg/ml) 10 µl (200 µg/ml) $121.00 $461.00 Qty: Bulk Request Product Details Applications Citations Product Details Specifications easley danceWebAnti-phospho-Histone H3 (Ser10) Antibody, Mitosis Marker is a Rabbit Polyclonal Antibody for detection of Histone H3 phosphorylated at serine 10.This highly published Ab, also known as Anti-H3S10p, ha More>> MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References easley cycleWebSep 12, 2012 · Phosphorylation of histone H3 on Ser10 in apoptotic cell death. ( A) and ( B) Jurkat (A) or HeLa (B) cells were treated with 1 mM hydroxyurea for 24 hours and then treated with cisplatin (50 µM) for the incubated times. Whole cell lysates were analyzed by immunoblotting with indicated antibodies. ct 薬剤師WebAnti-phospho-Histone H3 (Ser10) Antibody, clone MC463 is a rabbit monoclonal antibody for detection of Histone H3 phosphorylated at serine 10. This mAb, also known as H3S10p, is specificity verified using DB & Mplex, published in peer reviewed journals & validated in ChIP, IF, WB, ICC, ChIP-seq. Research Category Epigenetics & Nuclear Function ct 蔡司WebOur in silico data highlighted the potential interaction of MKP-1 with site-specific phospho-acetylated histone H3 at S10, K9 and K14 [23]. Earlier studies have demonstrated that MKP1 interacts ... easley deathsin november